Withdrawal from paroxetine can be severe, warns FDA -- Tonks 324 (7332): 260 -- BMJ

Withdrawal from paroxetine can be severe, warns FDA -- Tonks 324 (7332): 260 -- BMJ


Alison Tonks, Bristol The first 150 words of the full text of this article appear below.






http://www.bmj.com/cgi/content/extract/324/7332/260







GlaxoSmithKline, a leading drugs manufacturer, was last week forced to admit that paroxetine, a widely prescribed antidepressant and the company's best selling drug, can cause severe withdrawal symptoms when stopped.







The Food and Drug Administration in the United States published a new product warning about the drug, and in the same week the International Federation of Pharmaceutical Manufacturers Associations declared the company guilty of misleading the public about paroxetine on US television a year ago.







"This drug has been promoted for years as safe and easy to discontinue," said Charles Medawar, head of Social Audit, a consumer research group specialising in medicines policy. "The fact that it can cause intolerable withdrawal symptoms of the kind that could lead to dependence is enormously important to patients, doctors, investors, and the company.







"GlaxoSmithKline has evaded the issue since

SEROXAT SUFFERERS - STAND UP AND BE COUNTED: *** Exclusive - what it was really like for Fiddaman during cold turkey from Seroxat - here we bring you day 8

SEROXAT SUFFERERS - STAND UP AND BE COUNTED: *** Exclusive - what it was really like for Fiddaman during cold turkey from Seroxat - here we bring you day 8

SEROXAT SUFFERERS - STAND UP AND BE COUNTED: Day 8 and Fiddaman is clearly finding it a laugh !!

SEROXAT SUFFERERS - STAND UP AND BE COUNTED: Day 8 and Fiddaman is clearly finding it a laugh !!: "Day 8 and Fiddaman is clearly finding it a laugh !!
click on link below to personally verify this Bob Fiddaman Blogspot Exclusive ***"

Did West Mids Police Advise MH Drug Blogger On Blog Tactics ?

He said J Bryce is a GSK quisling - we say Mark Harvey of Hugh James is a liar

SEROXAT SUFFERERS - STAND UP AND BE COUNTED: He said J Bryce is a GSK quisling - we say Mark Harvey of Hugh James is a liar

GSK to appeal Kilker case - statement

GSK Statement on Jury Verdict in Paxil Product Liability Trial in Philadelphia Court of Common Pleas



http://bobfiddaman.blogspot.com/2009/10/gsk-to-appeal-kilker-case-statement.html















On October 13, 2009, a jury in the Philadelphia Court of Common Pleas returned a verdict against GlaxoSmithKline in a case alleging that Lyam Kilker was born with a rare heart defect as a result of his mothers use of Paxil during pregnancy.







GlaxoSmithKline disagrees with the verdict and will appeal. While we sympathize with Lyam Kilker and his family, the scientific evidence does not establish that exposure to Paxil during pregnancy caused his condition. Very unfortunately, birth defects occur in three to five percent of all live births, whether or not the mother was taking medication during pregnancy.







GlaxoSmithKline acted properly and responsibly in conducting its clinical trial program for Paxil, including sharing documentation and submitting results from studies on Paxil to regulators. Once approved for use, the company acted properly in marketing the medicine, including monitoring its safety, updating pregnancy information in the medicines labeling as new information became available, and in communicating important safety information to regulatory agencies, the scientific community and the public.

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Kevin Colgan
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Paxil Seroxat (birth defect) trial due to start today - "settled out of court last week"

Paxil Seroxat (birth defect) trial due to start today - "settled out of court last week"


Paxil (birth defect) trial due to start today - "settled out of court last week"
http://bobfiddaman.blogspot.com/2009/10/paxil-seroxat-birth-defect-trial-due-to.html


http://www.network54.com/Forum/281849/message/1255423909/Paxil+%28birth+defect%29+trial+due+to+start+today+-+%26quot%3Bsettled+out+of+court+last+week%26quot%3B







--------------------------------------------------------------------------------

A second Paxil case, expected to begin next Tuesday, was settled out of court last weekend. The next is not scheduled to begin in mid-November.



source - full report read on -



http://thestar.blogs.com/ethics/2009/10/first-paxil-trial-goes-to-the-jury.html



date - October 09, 2009